What significant event occurs during prophase?

Prepare for the Canadian National Institute of Health Entrance Exam. Study using flashcards and multiple-choice questions, each with hints and explanations. Ace your exam and advance in your academic journey at the CNIH!

During prophase, a crucial event is the condensation of chromatin into visible chromosomes, which involves the coiling of the chromatin structure. This is significant as it allows for the chromosomes to become more compact and easier to segregate during cell division. Additionally, during this phase, centrioles move toward opposite poles of the cell, setting the stage for the formation of the spindle apparatus that will be essential in the later stages of mitosis.

This movement is critical because it helps in the organization and eventual separation of sister chromatids during anaphase. The correct identification of prophase includes recognizing both the structural changes in chromatin and the spatial changes in cellular components, such as the centrioles moving apart. The formation of spindle fibers and their attachment to the centromeres happens in subsequent stages, but the initial coiling of chromatin and centriole movement is characteristic of prophase itself.

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