What is primarily duplicated during DNA replication?

Prepare for the Canadian National Institute of Health Entrance Exam. Study using flashcards and multiple-choice questions, each with hints and explanations. Ace your exam and advance in your academic journey at the CNIH!

During DNA replication, the primary objective is to duplicate the genetic material contained within the DNA, which is organized into structures known as chromosomes. Each chromosome is made up of a long strand of DNA, which contains the genetic instructions necessary for the functioning and development of an organism.

The process begins with the unwinding of the double helix structure of DNA, facilitated by enzymes such as helicase. This allows the two strands to separate, creating a template for the formation of new complementary strands. DNA polymerase then synthesizes new strands by adding nucleotides—these are the building blocks of DNA—complementary to the exposed bases on the template strands.

While nucleotides are essential as the components that are assembled to form new DNA strands, it is the entire chromosomes that are ultimately duplicated during the replication process. Proteins are involved in the machinery of replication and in the interactions with DNA but are not the direct focus of duplication. RNA may be synthesized during the process, such as messenger RNA, but it is not duplicated in the way that chromosomes are.

Thus, the correct answer reflects the fact that chromosomes, which carry the complete set of genetic information, are what undergo replication to ensure that each daughter cell inherits the same genetic material as the

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