What is peptidoglycan?

Prepare for the Canadian National Institute of Health Entrance Exam. Study using flashcards and multiple-choice questions, each with hints and explanations. Ace your exam and advance in your academic journey at the CNIH!

Peptidoglycan is a vital component of the cell wall in many bacteria, and its presence is significant for both structural integrity and classification purposes. It is a polymer that consists of a repeating unit of sugars and amino acids, forming a mesh-like structure that provides rigidity to bacterial cell walls. This structure is crucial for maintaining the shape of the bacteria and protecting them from osmotic pressure.

The importance of peptidoglycan in classification arises from the differences in the thickness and composition of peptidoglycan layers between Gram-positive and Gram-negative bacteria. Gram-positive bacteria have a thick peptidoglycan layer, which retains the crystal violet stain used in Gram staining, leading to their purple appearance under a microscope. In contrast, Gram-negative bacteria have a thinner peptidoglycan layer covered by an outer membrane, causing them to appear pink after the staining process. This characteristic plays a foundational role in microbiology for distinguishing between different types of bacteria.

Other options do not accurately reflect the nature of peptidoglycan. It is not a lipid, nor is it found exclusively in eukaryotic cells, as it is primarily associated with prokaryotic cells like bacteria. Additionally, it is not a type of protein that

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